The drive from Fort Scott to Des Moines is approximately 500 kilometers. The most efficient route takes you through Missouri and Iowa via US-69 and I-35. This journey takes about 5 hours of driving time. You will pass through the rolling plains of the Midwest before reaching the vibrant city of Des Moines.
Total Distance: 500 km driving, 450 km air distance.
Traffic in Des Moines can be heavy; plan accordingly.
Summer and fall for mild weather.