The trip from Highlands to Nashville covers 420 kilometers, crossing the Appalachian Mountains into Tennessee. You will take US-64 W to US-74 W, then merge onto I-40 W toward Nashville. The drive typically takes 5 hours. This route offers stunning mountain scenery before transitioning into the rolling hills of Middle Tennessee. It is a major cross-country corridor.
Total Distance: 420 km driving distance; 350 km straight-line air distance.
Stop in Knoxville for a break.
Spring or fall to enjoy the mild weather in Nashville.