The drive from Jefferson to Cincinnati is approximately 750 kilometers, primarily following the I-75 North corridor. You will pass through Atlanta, Chattanooga, Knoxville, and Lexington before reaching Cincinnati. This is a major interstate route that takes about 8 hours. It is a very common path for travelers heading into the Midwest.
Total Distance: 750 km driving distance; 670 km straight-line air distance.
I-75 through Kentucky is well-maintained but watch for speed traps.
June to August for riverfront events and outdoor festivals.