Knoxville
Knoxville
Kansas City
Kansas City
Flight Driving

Knoxville to Kansas City

Updated: 01 Jun 2026

The drive from Knoxville to Kansas City is a long trip west through the heart of the country. Covering approximately 1,200 kilometers, the route follows I-40 West to I-70 West. This drive takes about 12 to 14 hours. Flying from McGhee Tyson Airport (TYS) to Kansas City International Airport (MCI) is also an option, usually involving a connection. Kansas City is known for its barbecue, jazz history, and fountains. Plan your drive to avoid traffic in St. Louis.

Total Distance: Driving distance 1,250 km, straight-line air distance 1,050 km.
Fastest Way
Flying is the fastest, taking about 5 hours total.
Cheapest Way
Driving is the most cost-effective method for this trip.
Compare Knoxville to Kansas City Routes
Flight
Connecting
Driving
Direct
Duration 5 hours 13 hours
Avg Price $250 - $450 $180 - $250 in fuel
Operator American Airlines Personal Vehicle
Route TYS to MCI via CLT or ORD. I-40 W to I-70 W through St. Louis.
Tip Flights are convenient but require a layover. Traffic in St. Louis can be heavy during rush hour.
Travel Tips
  • Navigation
    Use a GPS to navigate the highway interchanges in St. Louis.
  • Parking
    Downtown parking is plentiful but can be pricey during events.
  • Weather
    Be prepared for cold winters and warm summers.
  • Dining
    Try the local barbecue while visiting.
  • Airport
    MCI is located about 25 minutes from downtown by car.
Safety Tips
  • Road Safety
    Be alert for heavy traffic on I-70.
  • Urban Safety
    Stick to well-lit areas when exploring downtown at night.
  • Vehicle Security
    Keep your car locked and avoid leaving valuables inside.
  • Emergency Prep
    Keep a first aid kit and water in your car.
People Also Ask
  • Is Kansas City safe?
    Yes, it is generally safe for visitors in tourist areas.
  • How long is the drive?
    Expect 12 to 14 hours of driving time.
  • Are there direct flights?
    No, direct flights are not currently available.
  • What is the best way to get around?
    A car is recommended for exploring the city.
  • Is the BBQ worth it?
    Yes, it is a legendary culinary experience.
Quick Info
  • From Knoxville, Tennessee, United States
  • To Kansas City, Missouri, United States
  • Modes
Best Time to Travel

Spring and autumn for pleasant weather to explore the city.

Things to Do in Kansas City
1
National WWI Museum and Memorial
A world-class museum dedicated to the history of the First World War.
2
Country Club Plaza
A historic shopping and dining district with beautiful architecture.
3
American Jazz Museum
A fascinating museum dedicated to the history of jazz music.
4
Kansas City BBQ
Try the famous local barbecue at one of the many renowned restaurants.
Tags
Knoxville to Kansas City driving to Kansas City flights to Kansas City I-40 to I-70 traveling to Missouri TYS to MCI road trip Knoxville to Kansas City best travel options