La Crosse
La Crosse
Minneapolis
Minneapolis
Train Driving

La Crosse to Minneapolis

Updated: 31 May 2026

The journey from La Crosse to Minneapolis is approximately 160 miles. You can take the Amtrak Empire Builder train, which offers a scenic ride along the Mississippi River, or drive via I-90 and US-52. The train takes about 3 hours, while driving takes roughly 2.5 to 3 hours. Both options are highly practical and popular for this route.

Total Distance: 257 km driving, 220 km air distance.
Fastest Way
Driving is slightly faster, taking about 2 hours 45 minutes.
Cheapest Way
Amtrak is often the most cost-effective and relaxing way to travel.
Compare La Crosse to Minneapolis Routes
Train
Direct
Driving
Direct
Duration 3 hours 2 hours 45 mins
Avg Price $25-$50 $30-$40 in fuel
Operator Amtrak Empire Builder Personal Vehicle
Route La Crosse Station to St. Paul-Minneapolis Union Depot I-90 W to US-52 N
Tip Book tickets in advance for the best fares. Check road conditions in winter as snow can impact travel time.
Travel Tips
  • Train Booking
    Book your Amtrak ticket early to secure a seat.
  • Driving
    Be prepared for potential traffic delays entering the Twin Cities.
  • Weather
    Check the forecast, as Minnesota winters can be harsh.
  • Parking
    Use public parking garages in downtown Minneapolis.
  • Navigation
    Use a GPS to navigate the city's highway system.
Safety Tips
  • Winter Driving
    Ensure your vehicle is equipped for snow if driving in winter.
  • Train Safety
    Follow all instructions from Amtrak staff.
  • City Safety
    Be aware of your surroundings in urban areas.
  • Emergency Kit
    Keep a winter emergency kit in your car.
People Also Ask
  • Is there a train?
    Yes, the Amtrak Empire Builder runs between La Crosse and St. Paul.
  • How long is the drive?
    It takes about 2.5 to 3 hours.
  • What is the best way to travel?
    Both train and car are excellent options.
  • Are there tolls?
    There are no major toll roads on this route.
  • Is it a scenic route?
    Yes, the train ride along the Mississippi is very beautiful.
Quick Info
  • From La Crosse, Wisconsin, United States
  • To Minneapolis, Minnesota, United States
  • Modes
Best Time to Travel

Summer for outdoor activities or winter for snow sports.

Things to Do in Minneapolis
1
Mall of America
Visit the largest mall in the US, featuring an indoor theme park and aquarium.
2
Minnehaha Falls
Explore this beautiful waterfall located in a city park.
3
Minneapolis Institute of Art
View extensive art collections from around the world.
4
Chain of Lakes
Enjoy walking, biking, or kayaking on the city's beautiful lakes.
Tags
La Crosse to Minneapolis train Amtrak Empire Builder driving to Minneapolis La Crosse to Minneapolis distance travel from La Crosse WI Minneapolis travel guide fastest way to Minneapolis Wisconsin to Minnesota travel