La Crosse
La Crosse
St. Paul
St. Paul
Train Driving

La Crosse to St. Paul

Updated: 31 May 2026

The journey from La Crosse to St. Paul is approximately 150 miles. You can take the Amtrak Empire Builder train, which offers a scenic ride along the Mississippi River, or drive via I-90 and US-52. The train takes about 3 hours, while driving takes roughly 2.5 to 3 hours. Both options are highly practical and popular for this route.

Total Distance: 241 km driving, 210 km air distance.
Fastest Way
Driving is slightly faster, taking about 2 hours 45 minutes.
Cheapest Way
Amtrak is often the most cost-effective and relaxing way to travel.
Compare La Crosse to St. Paul Routes
Train
Direct
Driving
Direct
Duration 3 hours 2 hours 45 mins
Avg Price $25-$50 $30-$40 in fuel
Operator Amtrak Empire Builder Personal Vehicle
Route La Crosse Station to St. Paul-Minneapolis Union Depot I-90 W to US-52 N
Tip Book tickets in advance for the best fares. Check road conditions in winter as snow can impact travel time.
Travel Tips
  • Train Booking
    Book your Amtrak ticket early to secure a seat.
  • Driving
    Be prepared for potential traffic delays entering the Twin Cities.
  • Weather
    Check the forecast, as Minnesota winters can be harsh.
  • Parking
    Use public parking garages in downtown St. Paul.
  • Navigation
    Use a GPS to navigate the city's highway system.
Safety Tips
  • Winter Driving
    Ensure your vehicle is equipped for snow if driving in winter.
  • Train Safety
    Follow all instructions from Amtrak staff.
  • City Safety
    Be aware of your surroundings in urban areas.
  • Emergency Kit
    Keep a winter emergency kit in your car.
People Also Ask
  • Is there a train?
    Yes, the Amtrak Empire Builder runs between La Crosse and St. Paul.
  • How long is the drive?
    It takes about 2.5 to 3 hours.
  • What is the best way to travel?
    Both train and car are excellent options.
  • Are there tolls?
    There are no major toll roads on this route.
  • Is it a scenic route?
    Yes, the train ride along the Mississippi is very beautiful.
Quick Info
  • From La Crosse, Wisconsin, United States
  • To St. Paul, Minnesota, United States
  • Modes
Best Time to Travel

Summer for outdoor activities or winter for snow sports.

Things to Do in St. Paul
1
Minnesota State Capitol
Visit the beautiful capitol building with its impressive dome.
2
Science Museum of Minnesota
Explore this interactive museum for all ages.
3
Como Park Zoo and Conservatory
Enjoy this free, family-friendly zoo and conservatory.
4
Mississippi National River and Recreation Area
Explore the riverfront and its history.
Tags
La Crosse to St. Paul train Amtrak Empire Builder driving to St. Paul La Crosse to St. Paul distance travel from La Crosse WI St. Paul travel guide fastest way to St. Paul Wisconsin to Minnesota travel