Train
Driving
Lewes to Buffalo
Updated: 28 May 2026
The drive from Lewes to Buffalo takes you north through the Pennsylvania Turnpike and then onto I-90 (the New York State Thruway). The 650 km trip takes about 7 hours. Alternatively, you can take a train from Wilmington to Buffalo via Amtrak, which is a comfortable and scenic option.
Total Distance: 650 km driving, 550 km air distance.
Fastest Way
Driving is the fastest, taking 7 hours.
Cheapest Way
Driving is the most cost-effective.
Compare Lewes to Buffalo Routes
|
Connecting
|
Direct
|
|
|---|---|---|
| Duration | 9 hours | 7 hours |
| Avg Price | $100-$250 | $80-$120 in fuel |
| Operator | Amtrak | Personal Vehicle |
| Route | Wilmington to Buffalo. | I-76 West to I-90 West. |
| Tip | Book in advance for the best rates. | Be prepared for tolls. |
Travel Tips
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TrafficI-90 can be busy; plan accordingly.
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TollsBe prepared for tolls in New York and Pennsylvania.
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ParkingDowntown Buffalo has many parking garages.
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WalkingThe downtown area is very walkable.
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WeatherWinters can be cold and snowy; pack accordingly.
Safety Tips
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DrivingStay alert in heavy traffic.
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EmergencyDial 911 for assistance.
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ValuablesKeep your car locked and valuables out of sight.
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Night SafetyStick to well-lit areas at night.
People Also Ask
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Is there a direct train?Yes, Amtrak runs direct trains from Wilmington to Buffalo.
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How long is the drive?About 7 hours.
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Is Buffalo safe?Yes, the downtown area is generally safe.
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What is the best time to visit?Summer is beautiful.
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Are there tolls?Yes, on the route through NY and PA.
Quick Info
- From Lewes, Delaware, United States
- To Buffalo, New York, United States
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Modes
Best Time to Travel
Summer for the beautiful weather and proximity to Niagara Falls.
Things to Do in Buffalo
1
Niagara Falls
A world-famous natural wonder just a short drive from Buffalo.
2
Buffalo and Erie County Botanical Gardens
A beautiful conservatory with a diverse collection of plants.
3
Albright-Knox Art Gallery
A world-class art museum with a diverse collection.
4
Canalside
A vibrant waterfront area with shops, restaurants, and activities.
Tags
Lewes to Buffalo
driving to Buffalo
train to Buffalo
I-90 route
Delaware to New York
upstate New York
travel guide
weekend trip
