Is there a train to Indianapolis?

Amtrak's Cardinal service serves Indianapolis's Union Station.

What is the best airport?

Indianapolis International Airport (IND) is the only major airport serving the region.

Yes, Indianapolis is a car-centric city and public transit is limited for tourists.

How long is the flight?

A flight with a connection typically takes 3 to 5 hours.

Is Indianapolis expensive?

No, Indianapolis is generally more affordable than many other major US cities.

Lexington

Indianapolis

Flight Driving

Lexington to Indianapolis

Updated: 31 May 2026

The journey from Lexington, South Carolina to Indianapolis, Indiana covers approximately 600 miles. Flying from Columbia Metropolitan Airport (CAE) to Indianapolis International Airport (IND) is the most efficient method, usually requiring a connection. Driving takes roughly 9 hours via I-26 W and I-65 N. You will cross the Appalachian Mountains and the heart of the Midwest. This route takes you from the humid South to the capital city of Indiana.

Total Distance: 960 km driving; 800 km air distance.

Fastest Way

Flying from CAE to IND takes approximately 4 hours including a layover.

Cheapest Way

Driving is the most cost-effective option for groups of two or more.

Compare Lexington to Indianapolis Routes

	Flight Connecting	Driving Direct
Duration	4 hours	9 hours
Avg Price	$200-$450	$120 in fuel
Operator	American Airlines	Personal Vehicle
Route	CAE to CLT to IND	I-26 W to I-65 N
Tip	Book flights arriving at IND to utilize the airport shuttle into downtown.	Plan for heavy traffic when entering the Indianapolis metropolitan area.

Travel Tips

Public Transit
The IndyGo bus system is a convenient way to get around the downtown area.
Dining
Try the local pork tenderloin sandwich, an Indiana staple.
Walking
Downtown Indianapolis is walkable, but be prepared for some hills.
Booking
Book popular attractions like the Children's Museum online to avoid long lines.
Weather
Indianapolis weather can be very cold in the winter; check the forecast before you go.

Safety Tips

Urban Awareness
Stay alert in downtown areas at night, especially near the entertainment districts.
Weather
Be cautious of severe winter storms and icy roads during the winter months.
Emergency Prep
Keep a basic emergency kit in your car if you are driving across the mountains.
Navigation
Use real-time traffic apps to navigate around freeway accidents.