The drive from Lexington to Myrtle Beach is approximately 250 kilometers. The most direct route is via I-26 and US-501, taking you to the coast. Expect about 3 hours of driving time. This is a popular route for a beach vacation.
Total Distance: 250 km driving, 220 km air distance.
Traffic can be heavy near Myrtle Beach during peak tourist season.
May to September for beach weather.