Is there a train to SF?

Amtrak's California Zephyr ends in Emeryville, where you can take a bus across the bridge.

What is the best airport?

SFO is the primary airport, but Oakland (OAK) is a viable alternative.

No, a car is a liability in San Francisco due to parking costs and traffic.

How long is the flight?

A flight with a connection typically takes 8 to 10 hours.

Yes, San Francisco is one of the most expensive cities in the United States.

Lexington

San Francisco

Flight Driving

Lexington to San Francisco

Updated: 31 May 2026

The journey from Lexington, South Carolina to San Francisco, California covers over 2,800 miles. Flying from Columbia Metropolitan Airport (CAE) to San Francisco International Airport (SFO) is the most practical option, requiring a connection. Driving is a multi-day journey taking roughly 42 hours via I-40 W and I-80 W. You will cross the heart of the country and the Sierra Nevada mountains. This route takes you from the humid South to the cool, foggy climate of the Bay Area.

Total Distance: 4,500 km driving; 4,000 km air distance.

Fastest Way

Flying from CAE to SFO takes approximately 9 hours including a layover.

Cheapest Way

Flying is generally more cost-effective than the fuel and lodging costs for a 42-hour drive.

Compare Lexington to San Francisco Routes

	Flight Connecting	Driving Direct
Duration	9 hours	42 hours
Avg Price	$400-$900	$600 in fuel
Operator	United Airlines	Personal Vehicle
Route	CAE to DEN to SFO	I-40 W to I-80 W
Tip	Book flights arriving at SFO to utilize the BART train into the city.	Check for snow closures on I-80 through the Sierra Nevada during winter months.

Travel Tips

Layering
San Francisco weather is unpredictable; always carry a jacket, even in summer.
Public Transit
Use the cable cars and Muni buses to navigate the city's steep hills.
Parking
Parking is extremely expensive and difficult to find; use public transit whenever possible.
Walking
San Francisco is a very walkable city, but be prepared for steep inclines.
Safety
Avoid leaving any items in your car, as vehicle break-ins are common in tourist areas.

Safety Tips

Urban Safety
Be aware of your surroundings in the Tenderloin and parts of SoMa at night.
Earthquake Prep
Familiarize yourself with basic earthquake safety procedures upon arrival.
Driving
Be cautious of cyclists and pedestrians who have the right of way in the city.
Weather
The fog can reduce visibility significantly; drive slowly if you have a rental car.