The drive from Lexington to Birmingham is approximately 350 miles and takes about 5.5 hours. You will primarily use I-20 West, which provides a direct path through Georgia and into Alabama. This route is straightforward and passes through Atlanta, so plan your timing to avoid the city's notorious traffic. It is a popular route for business and leisure travel between the two states.
Total Distance: 565 km driving distance; 480 km straight-line air distance.
Try to pass through Atlanta between 10 AM and 2 PM to avoid heavy traffic.
Spring and Fall for mild weather and outdoor exploration.