How long is the drive?

It takes about 9 hours of driving time.

There is no direct passenger train service from Lexington to Memphis.

What is the best route?

I-20 West to I-22 West is the most direct route.

There are no major tolls on this route.

Memphis is safe in tourist areas, but use common sense at night.

Lexington

Memphis

Driving

Lexington to Memphis

Updated: 31 May 2026

The drive from Lexington to Memphis is approximately 600 miles and takes about 9 hours. You will take I-20 West to I-22 West, passing through Georgia, Alabama, and into Tennessee. This route is a popular corridor for those traveling between the two states. Expect a smooth drive with plenty of service stops along the way.

Total Distance: 965 km driving distance; 850 km straight-line air distance.

Fastest Way

Driving is the most practical method as there are no direct flights from Columbia to Memphis.

Cheapest Way

Driving is the most affordable way to reach Memphis from Lexington.

Compare Lexington to Memphis Routes

Driving

Direct

Duration

9 hours

Avg Price

$90-$120 in fuel

Operator

Personal Vehicle

Route

I-20 W to I-22 W

Stop in Birmingham for a quick break.

Travel Tips

Traffic
Memphis traffic is manageable, but avoid rush hour in the city center.
Dining
Memphis has a great food scene; try the local barbecue.
Navigation
I-22 is well-marked, but stay alert for lane changes.
Rest Stops
There are plenty of service stations along I-20 and I-22.
Parking
Downtown Memphis has many affordable parking lots near major attractions.

Safety Tips

Road Safety
Stay alert for heavy truck traffic on I-20 and I-22.
Vehicle Check
Check your tire pressure before the long drive.
Emergency
Keep a charged phone and a portable power bank in your car.
Visibility
Use your headlights during heavy rain, which is common in the region.