The drive from Mammoth Lakes to Henderson, Nevada, spans 480 kilometers and takes approximately 5 hours. You will travel south on US-395 to the I-15 corridor, which leads directly into the Las Vegas Valley. This route takes you through the scenic Eastern Sierra and across the Mojave Desert. Henderson is a major suburb of Las Vegas, offering a quieter alternative for lodging. Ensure your vehicle is prepared for high-speed desert driving.
Total Distance: 480 km driving distance; 380 km straight-line air distance.
I-15 is very busy on Friday afternoons and Sunday evenings.
Spring and Fall are best to avoid the extreme summer heat of the desert.