How far is Des Moines from Chicago?

It is about a 5-hour drive west of Chicago.

Does DSM have direct flights from the West Coast?

No, you will need to connect through a major hub.

What is the best way to get around Des Moines?

A car is recommended for regional travel, but the downtown area is accessible by shuttle.

Yes, the tourist and downtown areas are generally safe for visitors.

Millbrae

Des Moines

Flight

Millbrae to Des Moines

Updated: 28 May 2026

To travel from Millbrae to Des Moines, Iowa, fly from San Francisco International Airport to Des Moines International Airport. You will typically connect through a hub like Denver, Chicago, or Minneapolis. The distance is approximately 2,700 kilometers. Des Moines is the capital of Iowa and is known for its vibrant downtown, arts scene, and parks. Expect a full day of travel for this trip.

Total Distance: 2,750 km driving distance; 2,600 km straight-line air distance.

Fastest Way

Connecting flight with a short layover in a major hub.

Cheapest Way

Flight to Des Moines International Airport (DSM) booked in advance.

Compare Millbrae to Des Moines Routes

Flight

Connecting

Duration

7 hours

Avg Price

300-700 USD

Operator

United Airlines

Route

SFO to DSM via DEN or ORD.

Des Moines International Airport is about 10 minutes from downtown.

Travel Tips

Airport Transport
Use ride-sharing services to get from DSM to downtown Des Moines.
Local Transit
The D-Line shuttle is a convenient way to travel around downtown Des Moines.
Dining
Try the local food scene, including the famous Iowa pork tenderloin sandwich.
Weather
Winters are very cold; pack heavy winter gear if visiting between November and March.
Local Events
Check the city calendar for events at the Wells Fargo Arena.

Safety Tips

Winter Safety
Be cautious of icy sidewalks and roads during the winter months.
City Safety
The downtown and tourist areas are generally safe, but stay aware of your surroundings at night.
Emergency
Keep your phone charged and have a backup power bank for long days out.
Navigation
Use GPS for navigating the city's streets and highways.