The journey from Myrtle Beach to Charleston is approximately 100 miles along the South Carolina coast. Driving is the most practical and common method, taking about 2 hours via US-17 South. This route takes you through charming coastal towns and scenic landscapes, offering a relaxing drive through the Lowcountry. There is no direct train or bus service that is more efficient than driving.
Total Distance: 160 km driving distance; 140 km straight-line air distance.
Enjoy the scenic views along the coast, but be mindful of speed limits in small towns.
March to May or September to November for mild weather.