The drive from Orangeburg to Charleston, West Virginia is approximately 450 miles. You will head north on I-77, which takes you through the heart of the Appalachian mountains. Charleston is the capital of West Virginia and is known for its historic architecture.
Total Distance: 720 km driving distance; 600 km straight-line air distance.
The mountain passes on I-77 can be challenging; drive carefully.
Fall for the spectacular autumn foliage.