The journey from Portsmouth to Washington, D.C. covers approximately 450 miles. Most travelers take a bus to Boston and then fly from Logan Airport or take an Amtrak train from South Station. The total travel time is roughly 6 to 8 hours. You will pass through major cities like New York and Philadelphia along the way. This route is common for government and business travel.
Total Distance: 720 km driving, 630 km air distance.
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| Duration | 8 hours | 4 hours (including airport time) |
| Avg Price | 120-250 USD | 150-300 USD |
| Operator | Amtrak | JetBlue / American Airlines |
| Route | Bus to Boston, then Amtrak Northeast Regional to Union Station. | Bus to Boston Logan, flight to DCA or IAD. |
| Tip | The train is more comfortable and offers city-center to city-center service. | Fly into Reagan National (DCA) for the easiest access to downtown DC. |
Spring for the Cherry Blossom Festival or Autumn for mild weather.