The journey from Sioux Falls to San Diego is best accomplished by flying from Sioux Falls Regional Airport (FSD) to San Diego International Airport (SAN). Driving is a massive undertaking of over 1,700 miles across the central and western United States. San Diego is a beautiful coastal city known for its beaches, parks, and mild weather. Expect a significant change in climate as you move from the plains to the coast.
Total Distance: Driving distance 2,700 km, Air distance 2,300 km.
San Diego International Airport is very close to downtown.
March to May or September to November for pleasant weather.