The drive from Sturgeon Bay to Des Moines covers 600 kilometers and takes approximately 6 hours. You will head south on WI-57 to Green Bay, then take I-41 to Milwaukee, I-94 to Chicago, and finally I-80 West to Des Moines. This is a long but straightforward route that takes you through some of the major cities of the Midwest. It is a popular path for those traveling for business or visiting family.
Total Distance: 600 km driving distance; 450 km straight-line air distance.
The drive through Chicago can be very busy; try to avoid rush hour.
Spring or autumn for the pleasant weather.