The route from Tyler to Amarillo spans 850 kilometers, taking you from the Piney Woods into the high plains of the Texas Panhandle. The most direct path is via US-287 North, which bypasses the Dallas-Fort Worth metroplex. Expect a driving time of approximately 9 hours. You will experience a dramatic change in elevation and landscape as you approach the Panhandle.
Total Distance: 850 km driving distance; 720 km straight-line air distance.
US-287 is a major trucking route; stay alert for heavy traffic.
May to September for warmer weather, though be prepared for sudden thunderstorms.