Driving
Vicksburg to Biloxi
Updated: 29 May 2026
The drive from Vicksburg to Biloxi covers approximately 320 km. The most direct route is via US-49 S, which takes about 3.5 hours. You will pass through the heart of Mississippi, experiencing the diverse landscapes of the region before reaching the Gulf Coast. This is a straightforward drive, perfect for a day trip or a weekend getaway. Expect moderate traffic as you approach the Biloxi area.
Total Distance: 320 km driving, 290 km air distance.
Fastest Way
Driving via US-49 S takes approximately 3.5 hours.
Cheapest Way
Driving is the only practical way to travel between these two cities.
Compare Vicksburg to Biloxi Routes
Driving
Direct
Duration
3 hours 30 mins
Avg Price
$40 - $60 in fuel
Operator
Personal Vehicle
Route
US-49 S
US-49 is a well-maintained highway; watch for speed traps in small towns.
Travel Tips
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Route PlanningUS-49 S is the most direct route; check for road construction before leaving.
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FuelingFill up your tank in Vicksburg before starting the drive.
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DiningEnjoy a meal at one of the seafood restaurants in Biloxi.
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ParkingParking is generally easy to find in Biloxi.
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WeatherMississippi can be very humid; dress accordingly.
Safety Tips
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Driving SafetyStay alert for wildlife on rural stretches of US-49.
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Speed LimitsObserve speed limits strictly in small towns along the route.
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Vehicle CheckEnsure your vehicle is in good condition before the trip.
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Emergency PrepKeep a basic emergency kit in your car.
People Also Ask
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Is there a train?No, there is no direct rail service between Vicksburg and Biloxi.
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How long is the drive?The drive takes approximately 3.5 hours.
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What is the best way to get around Biloxi?A car is the most convenient way to explore the city.
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Is US-49 safe?Yes, it is a major highway, but be cautious of speed limits.
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What is the distance?The driving distance is approximately 320 km.
Quick Info
- From Vicksburg, Mississippi, United States
- To Biloxi, Mississippi, United States
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Modes
Best Time to Travel
Spring or Fall to enjoy the pleasant weather and the coastal breeze.
Things to Do in Biloxi
1
Biloxi Lighthouse
A historic lighthouse located on the Gulf Coast.
2
Beau Rivage Resort & Casino
A popular resort and casino on the Biloxi waterfront.
3
Maritime and Seafood Industry Museum
A museum dedicated to the history of the Gulf Coast seafood industry.
4
Biloxi Beach
A beautiful beach on the Gulf of Mexico.
Tags
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Vicksburg to Biloxi distance
