Ames
Ames
Columbus
Columbus
Flight Driving

Ames to Columbus

Updated: 28 May 2026

The journey from Ames to Columbus covers roughly 600 miles. You will typically fly from Des Moines (DSM) to John Glenn Columbus International Airport (CMH). If driving, the route follows I-80 East to I-71 South, taking you through Illinois and Indiana. This is a straightforward drive through the Midwest. Be prepared for heavy traffic in major cities along the route.

Total Distance: Driving distance 950 km, straight-line air distance 800 km.
Fastest Way
Flight from Des Moines (DSM) to Columbus (CMH), taking approximately 5 hours including connection.
Cheapest Way
Flight from Des Moines (DSM) to Columbus (CMH) booked at least 3 weeks in advance.
Compare Ames to Columbus Routes
Flight
Connecting
Driving
Direct
Duration 5 hours 9 hours
Avg Price $150 - $400 $150 - $300 (fuel/lodging)
Operator United Airlines Personal Vehicle
Route DSM to CMH I-80 E to I-71 S
Tip United Airlines offers frequent connections from Des Moines to Columbus via major hubs. Plan for a stop in Indianapolis to break up the drive.
Travel Tips
  • Transportation
    Rideshares are the most convenient way to get around Columbus, as parking downtown can be expensive.
  • Weather
    Columbus can have unpredictable weather; pack layers and a waterproof jacket.
  • Dining
    Try the local food scene, including the diverse restaurants in the Short North neighborhood.
  • Safety
    Stay aware of your surroundings in downtown areas, especially at night.
  • Sports
    Columbus is a major sports city; check the schedule for Ohio State University games.
Safety Tips
  • Urban Awareness
    Be mindful of your belongings in crowded tourist areas.
  • Emergency
    Keep your phone charged and know the location of the nearest medical facility.
  • Driving
    Traffic in Columbus can be heavy; use navigation apps to avoid delays.
  • Weather Safety
    If visiting in winter, be prepared for snow and icy road conditions.
People Also Ask
  • Is there a direct flight from Ames to Columbus?
    No, you must fly from Des Moines International Airport (DSM) with a connection.
  • How long is the drive from Ames to Columbus?
    It is approximately 9 hours of driving time, usually requiring one day.
  • What is the best way to get around Columbus?
    Rideshares are the most convenient option for most visitors.
  • Is Columbus expensive?
    It is relatively affordable compared to other major US cities.
  • What should I pack for Columbus?
    Layers and comfortable walking shoes are essential for the city's varied terrain.
Quick Info
  • From Ames, Iowa, United States
  • To Columbus, Ohio, United States
  • Modes
Best Time to Travel

May to June or September to October for mild weather.

Things to Do in Columbus
1
COSI (Center of Science and Industry)
Explore this world-class science museum featuring interactive exhibits for all ages. It is a must-visit for families.
2
German Village
Wander through this historic neighborhood filled with brick houses, charming shops, and excellent restaurants.
3
Franklin Park Conservatory
Admire the beautiful botanical gardens and glass art collections. It is a peaceful escape in the middle of the city.
4
Short North Arts District
Explore this vibrant neighborhood filled with art galleries, boutiques, and nightlife. It is the center of the city's social scene.
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