Is there a train to Tallahassee?

No, Amtrak does not serve Tallahassee directly.

How far is the drive?

The drive is approximately 1,900 kilometers.

What is the best airport?

Tallahassee International Airport (TLH) is the closest.

Are there direct flights?

No, all flights from DSM to TLH require at least one connection.

Is it safe to drive alone?

Yes, provided you stay on major interstates and plan your stops.

Ames

Tallahassee

Flight Driving

Ames to Tallahassee

Updated: 28 May 2026

Traveling from Ames to Tallahassee requires navigating through the heart of the United States. You can fly from Des Moines International Airport (DSM) to Tallahassee International Airport (TLH) with at least one layover. Driving is a long-haul journey of approximately 1,900 kilometers via I-35 and I-75. Tallahassee is the capital of Florida and is located in the Panhandle region. This route takes you through diverse landscapes including the rolling hills of the Midwest and the pine forests of the South.

Total Distance: Driving distance 1,900 km, straight-line air distance 1,500 km.

Fastest Way

Flying via Atlanta is the fastest, taking about 6 hours including layover.

Cheapest Way

Driving is the most cost-effective for multiple passengers.

Compare Ames to Tallahassee Routes

	Flight Connecting	Driving Direct
Duration	6 hours	19 hours
Avg Price	$350-$700	$220-$380 in fuel
Operator	Delta Air Lines	Personal Vehicle
Route	DSM to ATL to TLH.	I-35 S to I-75 S.
Tip	The connection in Atlanta is usually efficient for reaching Tallahassee.	Plan for an overnight stop in Birmingham, Alabama.

Travel Tips

Booking Flights
Check flights into Jacksonville or Panama City as alternatives if TLH prices are high.
Driving Breaks
Stop at rest areas every three hours to stretch your legs.
Navigation
Download offline maps as cell service can be spotty in rural Alabama.
Packing
Bring light clothing as Tallahassee is significantly warmer than Ames.
Rental Cars
If flying, book your rental car at TLH well in advance.

Safety Tips

Wildlife
Be cautious of deer on the road during dawn and dusk in rural areas.
Weather
Check for hurricane warnings if traveling during the summer or fall.
Vehicle Maintenance
Ensure your cooling system is in top shape for the Southern heat.
Communication
Keep a portable charger for your phone in case of emergencies.