Driving
Biloxi to Memphis
Updated: 28 May 2026
The drive from Biloxi to Memphis is approximately 600 kilometers. You will travel north through Mississippi, primarily using US-49. The trip takes about 6 hours. Memphis is famous for its music history, including Beale Street and Graceland. This route takes you through the heart of the Mississippi Delta.
Total Distance: 600 km driving, 520 km air distance.
Fastest Way
Driving is the fastest method for this route.
Cheapest Way
Driving is the most cost-effective way to reach Memphis.
Compare Biloxi to Memphis Routes
Driving
Direct
Duration
6 hours
Avg Price
$70-$100 in fuel
Operator
Personal Vehicle
Route
US-49 N.
Stop in Jackson for a break.
Travel Tips
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TrafficMemphis traffic is generally manageable.
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ParkingParking is available in downtown.
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FoodTry local Memphis-style barbecue.
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Rest StopsUse rest areas along US-49.
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NavigationUse GPS to navigate the city.
Safety Tips
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SpeedingWatch for speed traps in small towns.
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WeatherBe aware of potential storms in the South.
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VehicleCheck your tire pressure before the trip.
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EmergencyKeep a blanket and water in your car.
People Also Ask
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How long is the drive?It takes about 6 hours.
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Is there a train?No direct passenger train service is available.
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What is the best route?US-49 is the most efficient path.
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Is Memphis safe?Like any major city, exercise normal precautions.
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Are there tolls?There are no major tolls on this route.
Quick Info
- From Biloxi, Mississippi, United States
- To Memphis, Tennessee, United States
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Modes
Best Time to Travel
Spring or Fall for pleasant weather.
Things to Do in Memphis
1
Graceland
Visit the home of Elvis Presley.
2
Beale Street
Enjoy the music and nightlife.
3
National Civil Rights Museum
Learn about the history of the civil rights movement.
4
Sun Studio
Tour the famous recording studio.
Tags
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Mississippi to Tennessee road trip
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