Biloxi
Biloxi
San Antonio
San Antonio
Driving

Biloxi to San Antonio

Updated: 28 May 2026

Traveling from Biloxi to San Antonio involves a straight shot west along the I-10 corridor. You will traverse the entire length of the Louisiana coast and cross the Texas border. The drive covers roughly 820 kilometers and takes about 8 hours of pure driving time. San Antonio is famous for its colonial history and the iconic River Walk. This route is ideal for those who enjoy scenic coastal views followed by vast Texas landscapes.

Total Distance: 820 km driving, 750 km air distance.
Fastest Way
Driving is the fastest way as there are no direct flights from Biloxi to San Antonio.
Cheapest Way
Driving your own vehicle is the most cost-effective method for this route.
Compare Biloxi to San Antonio Routes
Driving
Direct
Duration
8 hours
Avg Price
$110-$160 in fuel
Operator
Personal Vehicle
Route
I-10 West through Baton Rouge, Lafayette, and Houston.

Stop in Lafayette for authentic Cajun food.

Travel Tips
  • Traffic
    Avoid Houston during rush hour to save two hours of travel time.
  • Dining
    Try the Tex-Mex cuisine; it is a staple of the local culture.
  • Walking
    Wear comfortable shoes as the River Walk covers several miles.
  • Parking
    Use the city-run parking garages near the River Walk for lower rates.
  • Language
    Spanish is widely spoken; basic phrases are helpful.
Safety Tips
  • Heat Safety
    Stay hydrated during the summer months when temperatures exceed 100 degrees.
  • Vehicle Security
    Do not leave valuables in your car when parked in downtown areas.
  • Road Conditions
    Check for construction updates on I-10 before departing.
  • Emergency
    Keep a physical map in case GPS fails in remote areas.
People Also Ask
  • Is San Antonio walkable?
    The downtown area and River Walk are very walkable.
  • How far is the drive?
    It is approximately 820 kilometers.
  • Are there trains?
    No, there is no direct passenger rail service.
  • What is the best time to visit?
    Spring and Fall are the most comfortable seasons.
  • Is it safe?
    Yes, San Antonio is generally safe for tourists in popular areas.
Quick Info
  • From Biloxi, Mississippi, United States
  • To San Antonio, Texas, United States
  • Modes
Best Time to Travel

Autumn months of October and November provide pleasant weather for walking the city.

Things to Do in San Antonio
1
The Alamo
Visit the historic mission and fortress. It is the most visited site in Texas.
2
River Walk
Stroll along the river lined with restaurants and shops. It is best enjoyed in the evening.
3
San Antonio Missions
Explore the UNESCO World Heritage site featuring four historic Spanish missions.
4
Pearl District
Dine at the trendy culinary hub located in a former brewery complex.
Tags
Biloxi to San Antonio drive I-10 road trip San Antonio travel guide Mississippi to Texas travel driving to San Antonio Alamo visit River Walk tips fastest route to San Antonio