Yes, most tourist areas are safe, but stay aware of your surroundings.

What is the best way to get around?

A car is essential for exploring the mountains effectively.

Is the altitude a problem?

Yes, it can cause altitude sickness; drink plenty of water.

Are there many mountains?

Yes, the Rocky Mountains are a short drive away.

It is moderately priced compared to major coastal cities.

Des Moines

Denver

Flight Driving

Des Moines to Denver

Updated: 28 May 2026

The journey from Des Moines to Denver is a 900-kilometer trip west via Interstate 80. Driving is the most common method, taking approximately nine hours. Alternatively, you can fly from Des Moines International Airport (DSM) to Denver International Airport (DEN). Denver is known for its proximity to the Rocky Mountains, vibrant culture, and outdoor activities.

Total Distance: 900 km driving distance; 850 km straight-line air distance.

Fastest Way

Flight from DSM to DEN is the fastest, taking about 1.5 hours.

Cheapest Way

Driving is the most economical option for groups.

Compare Des Moines to Denver Routes

	Flight Direct	Driving Direct
Duration	1 hour 30 mins	9 hours
Avg Price	$150 - $300	$100 - $150 in fuel
Operator	United Airlines	Personal Vehicle
Route	DSM to DEN.	I-80 W to I-76 W.
Tip	Book tickets in advance for the best prices.	The drive is long and mostly flat until you reach the mountains.

Travel Tips

Altitude
Denver is at high altitude; drink plenty of water to avoid altitude sickness.
Transport
A car is recommended for exploring the mountains.
Culture
Explore the vibrant LoDo district.
Weather
Weather can change quickly; pack layers.
Events
Check the calendar for local festivals and events.

Safety Tips

General
Denver is generally safe, but stay aware of your surroundings in downtown at night.
Pedestrian Safety
Be cautious when crossing busy streets.
Emergency
Keep a water bottle with you at all times.
Public Transit
Stay alert on public transit, especially late at night.