Des Moines
Des Moines
Kansas City
Kansas City
Bus Driving

Des Moines to Kansas City

Updated: 28 May 2026

The journey from Des Moines to Kansas City is a 300-kilometer trip south via Interstate 35. Driving is the most convenient method, taking approximately three hours. The route is straightforward and passes through the heart of the Midwest. Kansas City is known for its jazz, barbecue, and beautiful fountains.

Total Distance: 300 km driving distance; 280 km straight-line air distance.
Fastest Way
Driving your own vehicle is the fastest way, taking about 3 hours.
Cheapest Way
Bus travel is the most economical option for solo travelers.
Compare Des Moines to Kansas City Routes
Bus
Direct
Driving
Direct
Duration 4 hours 3 hours
Avg Price $30 - $60 $40 - $60 in fuel
Operator Jefferson Lines Personal Vehicle
Route Des Moines to Kansas City. I-35 S.
Tip Book tickets in advance for the best prices. The drive is easy and mostly flat.
Travel Tips
  • Dining
    You must try the barbecue; it is the best in the country.
  • Transport
    A car is recommended for exploring the city effectively.
  • Culture
    Explore the jazz history in the 18th & Vine district.
  • Weather
    Summers are hot and humid; pack light clothing.
  • Events
    Check the calendar for local festivals and events.
Safety Tips
  • General
    Kansas City is generally safe, but stay aware of your surroundings in downtown at night.
  • Pedestrian Safety
    Be cautious when crossing busy streets.
  • Emergency
    Keep a water bottle with you at all times.
  • Public Transit
    Stay alert on public transit, especially late at night.
People Also Ask
  • Is Kansas City safe?
    Yes, most tourist areas are safe, but stay aware of your surroundings.
  • What is the best way to get around?
    A car is essential for exploring the area effectively.
  • Is the BBQ really that good?
    Yes, it is world-famous and a must-try for any visitor.
  • Are there many fountains?
    Yes, the city is known as the 'City of Fountains'.
  • Is it expensive?
    It is generally more affordable than major coastal cities.
Quick Info
  • From Des Moines, Iowa, United States
  • To Kansas City, Missouri, United States
  • Modes
Best Time to Travel

April to June or September to October for pleasant weather.

Things to Do in Kansas City
1
National WWI Museum and Memorial
A world-class museum dedicated to the history of the First World War. It is a must-visit.
2
Country Club Plaza
A beautiful outdoor shopping and dining district with Spanish-inspired architecture. It is a great place to walk.
3
Kansas City BBQ
Try the world-famous barbecue; it is a local staple and a must-try.
4
Nelson-Atkins Museum of Art
A renowned art museum with a vast collection. Admission is free.
Tags
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