The drive from Des Peres to Kansas City is a 400 km journey across the state of Missouri. You will primarily follow I-70 W, passing through Columbia. The trip takes approximately 4 hours. This route is a major corridor connecting the two largest cities in Missouri.
Total Distance: 400 km driving distance; 370 km straight-line air distance.
Stop in Columbia for a coffee break.
Spring and Fall for comfortable driving weather.