The journey from Mt Vernon to Pittsburgh is a 500-mile trip that takes approximately 8 hours via I-70. This route takes you through the heart of the Midwest and into Pennsylvania. It is a popular route for those traveling between the Midwest and the East Coast.
Total Distance: 800 km driving distance; 700 km straight-line air distance.
Expect heavy traffic in the Pittsburgh area.
Spring and Fall offer the best weather for visiting Pittsburgh.