Murrells Inlet
Murrells Inlet
Cleveland
Cleveland
Flight Driving

Murrells Inlet to Cleveland

Updated: 28 May 2026

Traveling from the South Carolina coast to Cleveland is best done by car or flight. Driving takes about 11 hours via I-77. Flights from Myrtle Beach International Airport are often connecting. The total flight time is approximately 5 to 6 hours. You will arrive at CLE, located southwest of the city.

Total Distance: Driving distance 1,050 km, air distance 900 km.
Fastest Way
Direct flight from MYR to CLE, total time 2 hours.
Cheapest Way
Driving your own vehicle.
Compare Murrells Inlet to Cleveland Routes
Flight
Direct
Driving
Direct
Duration 5 hours 11 hours
Avg Price 250-500 USD 180-250 USD (fuel)
Operator Frontier Airlines Personal Vehicle
Route MYR to CLE. I-77 N.
Tip Direct flights are seasonal; check schedules. Expect heavy traffic near Charlotte and Pittsburgh.
Travel Tips
  • Driving
    Be prepared for long stretches of highway driving.
  • Public Transit
    Use the RTA rapid transit system for city travel.
  • Dining
    Try the local Polish and Eastern European cuisine.
  • Weather
    Prepare for cold, snowy winters.
  • Parking
    Use parking garages in the downtown area.
Safety Tips
  • Driving Safety
    Stay alert for construction zones on I-77.
  • Pedestrian Safety
    Use crosswalks in the busy downtown area.
  • Winter Driving
    Be cautious of lake-effect snow during winter.
  • Emergency
    Keep a roadside emergency kit in your car.
People Also Ask
  • Is driving better than flying?
    Driving is cheaper, but flying is much faster.
  • How long is the drive?
    Expect about 11 hours of driving time.
  • Are there tolls?
    Some routes may have tolls, check your GPS.
  • What is the best airport?
    Cleveland Hopkins International Airport.
  • Is it safe to walk?
    Yes, downtown is generally safe and walkable.
Quick Info
  • From Murrells Inlet, South Carolina, United States
  • To Cleveland, Ohio, United States
  • Modes
Best Time to Travel

June to September for pleasant weather.

Things to Do in Cleveland
1
Rock & Roll Hall of Fame
Visit the iconic museum dedicated to rock music history.
2
West Side Market
Explore the historic public market for local food.
3
Cleveland Museum of Art
View world-class art collections in a beautiful setting.
4
Edgewater Park
Enjoy the beach and views of Lake Erie.
Tags
Murrells Inlet to Cleveland driving to Cleveland from SC flights to CLE from SC traveling to Ohio Myrtle Beach to Cleveland Cleveland travel guide SC to OH travel best way to visit Cleveland CLE airport tips Midwest travel