Murrells Inlet
Murrells Inlet
Columbus
Columbus
Flight Driving

Murrells Inlet to Columbus

Updated: 28 May 2026

Traveling from the South Carolina coast to Columbus is best done by car or flight. Driving takes about 9 to 10 hours via I-77 and I-70. Flights from Myrtle Beach International Airport are often connecting. The total flight time is approximately 5 to 6 hours. You will arrive at CMH, located east of the city.

Total Distance: Driving distance 850 km, air distance 700 km.
Fastest Way
Direct flight from MYR to CMH, total time 2 hours.
Cheapest Way
Driving your own vehicle.
Compare Murrells Inlet to Columbus Routes
Flight
Connecting
Driving
Direct
Duration 5 hours 9 hours 30 mins
Avg Price 200-450 USD 140-200 USD (fuel)
Operator Southwest Airlines Personal Vehicle
Route MYR to CMH via BWI or MDW. I-77 N to I-70 W.
Tip Check for direct seasonal flights. Expect heavy traffic near Charlotte.
Travel Tips
  • Driving
    Be prepared for long stretches of highway driving.
  • Public Transit
    Use the COTA bus system for city travel.
  • Dining
    Try the local food scene in the Short North.
  • Weather
    Prepare for cold, snowy winters.
  • Parking
    Use parking garages in the downtown area.
Safety Tips
  • Driving Safety
    Stay alert for construction zones on I-70.
  • Pedestrian Safety
    Use crosswalks in the busy downtown area.
  • Winter Driving
    Be cautious of snow and ice during winter.
  • Emergency
    Keep a roadside emergency kit in your car.
People Also Ask
  • Is driving better than flying?
    Driving is cheaper, but flying is much faster.
  • How long is the drive?
    Expect about 9 to 10 hours of driving time.
  • Are there tolls?
    Some routes may have tolls, check your GPS.
  • What is the best airport?
    John Glenn Columbus International Airport.
  • Is it safe to walk?
    Yes, downtown is generally safe and walkable.
Quick Info
  • From Murrells Inlet, South Carolina, United States
  • To Columbus, Ohio, United States
  • Modes
Best Time to Travel

May to September for pleasant weather.

Things to Do in Columbus
1
COSI
Visit the Center of Science and Industry for interactive exhibits.
2
German Village
Explore the historic neighborhood with brick streets and shops.
3
Franklin Park Conservatory
View beautiful botanical gardens and glass art.
4
Short North Arts District
Enjoy galleries, boutiques, and restaurants.
Tags
Murrells Inlet to Columbus driving to Columbus from SC flights to CMH from SC traveling to Ohio Myrtle Beach to Columbus Columbus travel guide SC to OH travel best way to visit Columbus CMH airport tips Midwest travel