Murrells Inlet
Murrells Inlet
Pittsburgh
Pittsburgh
Flight Driving

Murrells Inlet to Pittsburgh

Updated: 28 May 2026

Traveling from the South Carolina coast to Pittsburgh can be done by car or flight. Driving takes about 10 to 11 hours via I-77 and I-79. Flights from Myrtle Beach International Airport are often connecting. The total flight time is approximately 4 to 5 hours. You will arrive at PIT, located west of the city.

Total Distance: Driving distance 950 km, air distance 800 km.
Fastest Way
Direct flight from MYR to PIT, total time 2 hours.
Cheapest Way
Driving your own vehicle.
Compare Murrells Inlet to Pittsburgh Routes
Flight
Direct
Driving
Direct
Duration 4 hours 10 hours 30 mins
Avg Price 200-400 USD 150-200 USD (fuel)
Operator Spirit Airlines Personal Vehicle
Route MYR to PIT. I-77 N to I-79 N.
Tip Direct flights are seasonal; check schedules. Expect tolls on the Pennsylvania Turnpike.
Travel Tips
  • Driving
    Be prepared for hilly terrain and many bridges.
  • Public Transit
    Use the T light rail system for downtown travel.
  • Dining
    Try the famous Primanti Bros sandwich.
  • Weather
    Bring an umbrella as rain is common throughout the year.
  • Parking
    Use parking garages in the city to avoid street parking stress.
Safety Tips
  • Driving Safety
    Watch for sudden lane changes in tunnel areas.
  • Pedestrian Safety
    Use crosswalks in busy downtown intersections.
  • Winter Driving
    Be cautious of ice on bridges during winter months.
  • Emergency
    Keep a roadside emergency kit in your car.
People Also Ask
  • Is driving better than flying?
    Driving is cheaper, but flying is much faster.
  • How long is the drive?
    Expect about 10 to 11 hours of driving time.
  • Are there tolls?
    Yes, expect tolls on the Pennsylvania Turnpike.
  • What is the best airport?
    Pittsburgh International Airport is the primary hub.
  • Is it safe to walk?
    Yes, downtown is very walkable.
Quick Info
  • From Murrells Inlet, South Carolina, United States
  • To Pittsburgh, Pennsylvania, United States
  • Modes
Best Time to Travel

May to September for pleasant outdoor weather.

Things to Do in Pittsburgh
1
Point State Park
Visit the confluence of the three rivers in downtown.
2
Duquesne Incline
Ride the historic funicular for views of the city skyline.
3
Andy Warhol Museum
Explore the largest museum dedicated to a single artist.
4
Strip District
Enjoy local food markets and unique shops.
Tags
Murrells Inlet to Pittsburgh driving to Pittsburgh from SC flights to PIT from SC traveling to Pennsylvania Myrtle Beach to Pittsburgh Pittsburgh travel guide SC to PA travel best way to visit Pittsburgh PIT airport tips East Coast travel