Is there a direct flight?

No, all flights from Myrtle Beach require at least one connection.

How long is the drive?

It takes approximately 35 hours of driving time.

What is the best time to visit?

Winter and spring offer the most comfortable temperatures.

Yes, Phoenix is not very walkable and public transit is limited.

Is it safe to drive across the desert?

Yes, but ensure your vehicle is well-maintained and you have plenty of water.

Myrtle Beach

Phoenix

Flight Driving

Myrtle Beach to Phoenix

Updated: 28 May 2026

The journey from Myrtle Beach to Phoenix spans roughly 3,500 kilometers. Flying into Phoenix Sky Harbor International Airport (PHX) is the most practical choice, as driving takes over 35 hours. If you choose to drive, you will traverse the southern United States via I-20 and I-10. This route takes you through the heart of the desert Southwest. Prepare for significant temperature changes as you move from the humid coast to the arid desert.

Total Distance: 3,500 km driving, 3,000 km air distance.

Fastest Way

Flying is the fastest, taking about 8 hours including layovers.

Cheapest Way

Flying is generally more economical than the high fuel and lodging costs of a 4-day drive.

Compare Myrtle Beach to Phoenix Routes

	Flight Connecting	Driving Direct
Duration	8 hours	35 hours
Avg Price	$400 - $700	$450 - $650 in fuel
Operator	Southwest Airlines	Personal Vehicle
Route	MYR to PHX via Dallas (DAL) or Atlanta (ATL).	I-20 West to I-10 West through Texas and New Mexico.
Tip	Southwest offers flexible booking options for this long-haul route.	The stretch of I-10 through West Texas is very remote; keep your gas tank full.

Travel Tips

Hydration
Drink water constantly; the desert air is extremely dehydrating.
Sun Protection
Wear a wide-brimmed hat and high-SPF sunscreen at all times.
Transport
Phoenix is a sprawling city; a rental car is essential for most visitors.
Timing
Avoid outdoor activities during the peak heat of the afternoon in summer.
Airport
Sky Harbor is very close to downtown; use the PHX Sky Train for easy terminal access.

Safety Tips

Heat Safety
Never leave children or pets in a parked car, even for a minute.
Driving
Watch for dust storms (haboobs) on I-10; pull over if visibility drops.
Emergency
Carry extra water in your vehicle at all times when driving in the desert.
Urban Safety
Stay aware of your surroundings in downtown areas at night.