Driving
Myrtle Beach to Winston-Salem
Updated: 28 May 2026
The trip from Myrtle Beach to Winston-Salem is a 350-kilometer journey. Driving via I-74 takes about 4 hours. Winston-Salem is a historic city in North Carolina, known for its tobacco and textile history.
Total Distance: 350 km driving, 300 km air distance.
Fastest Way
Driving is the fastest method.
Cheapest Way
Driving is the most practical and cheapest way.
Compare Myrtle Beach to Winston-Salem Routes
Driving
Direct
Duration
4 hours
Avg Price
40-60 dollars in fuel
Operator
Personal Vehicle
Route
I-74 W.
Expect a straightforward drive.
Travel Tips
-
WalkingDowntown is very walkable.
-
FoodTry the local Southern cuisine.
-
HistoryVisit the historic sites in the city.
-
ParkingParking is available in the city.
-
NatureEnjoy the local parks.
Safety Tips
-
General SafetyStay in well-lit areas at night.
-
Public TransitKeep your belongings secure.
-
DrivingBe prepared for local traffic.
-
EmergencyDial 911 for any emergency.
People Also Ask
-
How long is the drive?It takes about 4 hours.
-
Are there direct flights?No, there are no direct flights.
-
Is Winston-Salem walkable?Yes, the downtown area is pedestrian-friendly.
-
What is the best time to visit?Spring and fall are ideal.
-
Are there tolls?No, this route is toll-free.
Quick Info
- From Myrtle Beach, South Carolina, United States
- To Winston-Salem, North Carolina, United States
-
Modes
Best Time to Travel
Spring and Fall for pleasant weather.
Things to Do in Winston-Salem
1
Old Salem
Visit the historic Moravian settlement.
2
Reynolda House
Explore the art museum.
3
Downtown Winston-Salem
Enjoy the local shops and restaurants.
4
SciWorks
Visit the science center.
Tags
Myrtle Beach to Winston-Salem drive
travel to Winston-Salem
I-74
driving distance to Winston-Salem
best way to Winston-Salem
Winston-Salem travel guide
SC to NC travel
