Reno
Reno
Des Moines
Des Moines
Flight Driving

Reno to Des Moines

Updated: 28 May 2026

The journey from Reno to Des Moines covers approximately 2,400 kilometers. Flying from Reno-Tahoe International Airport (RNO) to Des Moines International Airport (DSM) is the most efficient method. Driving takes about 24 hours via I-80 E. This route takes you from the high desert of Nevada to the heart of Iowa.

Total Distance: Driving distance 2,450 km, straight-line air distance 2,100 km.
Fastest Way
Flight, with a total travel time of 6 hours including layovers.
Cheapest Way
Flight, if booked at least 21 days in advance.
Compare Reno to Des Moines Routes
Flight
Connecting
Driving
Direct
Duration 6 hours 24 hours
Avg Price $350 - $700 $350 - $550 in fuel
Operator United Airlines Personal Vehicle
Route RNO to DSM via hubs like DEN or ORD. I-80 E.
Tip Book flights on Tuesdays for the best rates. Plan for stops in Salt Lake City and Omaha.
Travel Tips
  • Time Zone
    Des Moines is in the Central Time Zone, two hours ahead of Reno.
  • Airport Transit
    Use rideshare services to travel from DSM airport to downtown Des Moines.
  • Driving Breaks
    Take regular breaks to avoid fatigue on long stretches of highway.
  • Packing
    Pack layers, as the weather in the Midwest can change quickly.
  • Navigation
    Use a reliable GPS app to navigate through major city traffic.
Safety Tips
  • Road Safety
    Be cautious of high winds when driving through the plains.
  • Emergency Kit
    Keep a basic emergency kit in your car for long-distance travel.
  • Personal Safety
    Stay aware of your surroundings in urban areas.
  • Flight Security
    Follow all TSA guidelines for carry-on items.
People Also Ask
  • Is there a direct flight?
    No, most flights from RNO to DSM require at least one connection.
  • How long is the drive?
    The drive is approximately 24 hours of pure driving time.
  • What is the best route?
    I-80 E is the primary highway for this route.
  • Are there hotels near DSM?
    Yes, there are several hotels located near the airport.
  • Is Reno a desert city?
    Yes, Reno is located in the high desert of Nevada.
Quick Info
  • From Reno, Nevada, United States
  • To Des Moines, Iowa, United States
  • Modes
Best Time to Travel

Spring and autumn for pleasant weather in both locations.

Things to Do in Des Moines
1
Iowa State Capitol
The historic capitol building in Des Moines, famous for its gold dome. It is a must-visit.
2
Greater Des Moines Botanical Garden
A beautiful botanical garden in Des Moines, featuring a wide variety of plants and flowers. It is a must-visit.
3
National Automobile Museum
Located in Reno, this museum features a massive collection of historic cars. It is a great stop before you leave.
4
Pappajohn Sculpture Park
A beautiful park in downtown Des Moines, featuring a wide variety of sculptures. It is a must-visit.
Tags
Reno to Des Moines travel Nevada to Iowa flights to DSM driving to Des Moines cross country travel Reno travel Des Moines travel best way to travel