The journey from Rhinelander to Appleton spans approximately 160 kilometers through the heart of the Northwoods. Driving via US-45 South is the primary and most efficient method of travel. You will pass through scenic towns like Antigo and Clintonville along the route. The trip typically takes about 2 hours depending on traffic conditions near the Fox Cities. This route is essential for those connecting to the larger regional hubs in Eastern Wisconsin.
Total Distance: 160 km driving, 145 km air distance.
Check for construction near the Shawano area before departing.
September and October for fall foliage viewing along the US-45 corridor.