The journey from Rhinelander to Chicago is a 550-kilometer drive south. You will take US-45 to I-41, then connect to I-94 into Chicago. The drive typically takes about 6 hours, depending on traffic in the Milwaukee and Chicago metropolitan areas. Chicago offers world-class museums, architecture, and dining. This is a popular route for those traveling from the Northwoods to the big city.
Total Distance: 550 km driving, 500 km air distance.
Expect heavy traffic near the Illinois border.
Late spring or early fall for pleasant weather in the city.