The drive from Winston-Salem to Denver is a major cross-country journey of 2,400 kilometers. You will primarily follow I-70 West across the heart of the United States. Expect a travel time of at least 22 hours of pure driving. This route takes you through the plains and into the Rocky Mountains.
Total Distance: 2,400 km driving, 2,100 km air distance.
Plan for at least one overnight stop in Kansas.
Summer or early Fall for clear mountain roads.