The drive from Winston-Salem to Minneapolis covers approximately 1,800 kilometers. You will travel north through Ohio, Indiana, and Wisconsin before entering Minnesota. The primary highways are I-77, I-90, and I-94. Expect a travel time of about 18 hours. This route takes you through the heart of the Midwest.
Total Distance: 1,800 km driving, 1,600 km air distance.
Plan for an overnight stop in Chicago.
Summer for the best weather.