The drive from Winston-Salem to Omaha covers approximately 1,600 kilometers. You will travel west through Kentucky, Illinois, and Iowa before entering Nebraska. The primary highways are I-70 and I-80. Expect a travel time of about 16 hours. This route takes you through the heart of the Midwest.
Total Distance: 1,600 km driving, 1,400 km air distance.
Plan for an overnight stop in St. Louis.
Spring or Fall for mild weather.