The drive from Winston-Salem to Phoenix is a massive 3,400-kilometer cross-country trek. You will primarily follow I-40 West across the southern United States. Expect a travel time of at least 32 hours of pure driving. This route takes you through the desert landscapes of the Southwest.
Total Distance: 3,400 km driving, 3,000 km air distance.
Plan for at least two overnight stops.
Winter or Spring to avoid extreme desert heat.