The journey from Cape Girardeau to Washington DC covers approximately 1,400 kilometers. Flying from St. Louis to Reagan National Airport (DCA) is the most efficient. Alternatively, you can take an Amtrak train from St. Louis to Washington DC, which is a scenic but long journey. Washington DC is home to the nation's most iconic monuments and museums. Plan your trip to enjoy the rich history of the capital.
Total Distance: 1,450 km driving distance; 1,200 km straight-line air distance.
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| Duration | 24 hours | 4 hours |
| Avg Price | $200 - $400 | $250 - $500 |
| Operator | Amtrak | American Airlines |
| Route | St. Louis to Chicago, then Capitol Limited to DC. | STL to DCA via a hub. |
| Tip | The train journey is scenic but requires a transfer in Chicago. | Reagan National is the most convenient airport for downtown DC. |
Spring for the Cherry Blossom Festival and autumn for mild weather.