Flight
Driving
Des Moines to Baltimore
Updated: 28 May 2026
The journey from Des Moines to Baltimore covers approximately 1,750 kilometers. Driving takes about 17 to 18 hours via I-80 and I-76. Flying is also an option with connections. This route takes you through the Midwest and into the Mid-Atlantic region, ending in the historic port city of Baltimore.
Total Distance: 1,750 km driving, 1,500 km air distance.
Fastest Way
Flying is the fastest, taking about 5.5 hours including airport time.
Cheapest Way
Driving is the most cost-effective for this distance.
Compare Des Moines to Baltimore Routes
|
Connecting
|
Direct
|
|
|---|---|---|
| Duration | 5 hours 30 mins | 17 hours 30 mins |
| Avg Price | $350-$600 | $250-$350 in fuel |
| Operator | Southwest Airlines | Personal Vehicle |
| Route | DSM to BWI. | I-80 East to I-76 East through Pennsylvania. |
| Tip | Book early to secure better rates on connecting flights. | The Pennsylvania Turnpike is a toll road; have an E-ZPass ready. |
Travel Tips
-
Public TransitThe Charm City Circulator is a free bus service that covers much of downtown.
-
DiningTry the local Maryland blue crabs; they are a Baltimore staple.
-
ParkingUse the ParkWhiz app to find affordable parking in downtown Baltimore.
-
SafetyStick to well-lit, populated areas when exploring downtown at night.
-
Water TaxiThe Baltimore Water Taxi is a fun and convenient way to get around the harbor.
Safety Tips
-
TrafficTraffic in the Baltimore-Washington area can be heavy; plan your route to avoid peak hours.
-
WeatherThe Mid-Atlantic can have humid summers; stay hydrated.
-
Vehicle SecurityAlways lock your car and remove valuables when parking in urban areas.
-
Emergency KitKeep a basic emergency kit in your car for long-distance driving.
People Also Ask
-
Is there a train?No, there is no direct passenger rail service from Des Moines to Baltimore.
-
How long is the drive?Expect 17 to 18 hours of driving time.
-
Are there direct flights?No, flights from Des Moines to Baltimore require a connection.
-
Is Baltimore safe?Like any major city, exercise caution and stay in tourist-friendly areas.
-
What is the best route?I-80 to I-76 is the most direct path.
Quick Info
- From Des Moines, Iowa, United States
- To Baltimore, Maryland, United States
-
Modes
Best Time to Travel
April to June or September to October for pleasant weather.
Things to Do in Baltimore
1
Inner Harbor
Visit the historic waterfront area with shops, restaurants, and attractions.
2
National Aquarium
Explore the world-class aquarium located in the Inner Harbor.
3
Fort McHenry National Monument
Learn about the history of the fort that inspired the national anthem.
4
Baltimore Museum of Art
Explore the extensive art collection, including works by Matisse.
Tags
Des Moines to Baltimore
flights to Baltimore
driving to Maryland
I-80 and I-76 route
travel Iowa to Maryland
Baltimore travel guide
Des Moines airport
Baltimore airport BWI
East Coast road trip
travel tips
