Flight
Driving
Des Moines to Birmingham
Updated: 28 May 2026
The journey from Des Moines to Birmingham covers approximately 1,450 kilometers. Driving takes about 14 to 15 hours via I-35 and I-65. Flying is also an option with connections. This route takes you through the Midwest and into the South, ending in the historic city of Birmingham.
Total Distance: 1,450 km driving, 1,250 km air distance.
Fastest Way
Flying is the fastest, taking about 5 hours including airport time.
Cheapest Way
Driving is the most cost-effective for this distance.
Compare Des Moines to Birmingham Routes
|
Connecting
|
Direct
|
|
|---|---|---|
| Duration | 5 hours | 14 hours 30 mins |
| Avg Price | $300-$550 | $200-$300 in fuel |
| Operator | American Airlines | Personal Vehicle |
| Route | DSM to CLT or BHM. | I-35 South to I-65 South through Nashville. |
| Tip | Book early to secure better rates on connecting flights. | Nashville is a great place to stop for a meal or a break. |
Travel Tips
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Public TransitThe BJCTA bus system is a convenient way to get around Birmingham.
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DiningTry the local Southern-inspired cuisine; it is a Birmingham staple.
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ParkingUse the ParkWhiz app to find affordable parking in downtown Birmingham.
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SafetyStick to well-lit, populated areas when exploring downtown at night.
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HistoryBirmingham is rich in history; take a walking tour to learn more.
Safety Tips
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TrafficTraffic in the Nashville area can be heavy; plan your route to avoid peak hours.
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WeatherThe South can have humid summers; stay hydrated.
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Vehicle SecurityAlways lock your car and remove valuables when parking in urban areas.
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Emergency KitKeep a basic emergency kit in your car for long-distance driving.
People Also Ask
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Is there a train?No, there is no direct passenger rail service from Des Moines to Birmingham.
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How long is the drive?Expect 14 to 15 hours of driving time.
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Are there direct flights?No, flights from Des Moines to Birmingham require a connection.
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Is Birmingham safe?Like any major city, exercise caution and stay in tourist-friendly areas.
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What is the best route?I-35 to I-65 is the most direct path.
Quick Info
- From Des Moines, Iowa, United States
- To Birmingham, Alabama, United States
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Modes
Best Time to Travel
April to June or September to October for pleasant weather.
Things to Do in Birmingham
1
Birmingham Civil Rights Institute
Learn about the history of the Civil Rights Movement in Birmingham.
2
Barber Vintage Motorsports Museum
Explore the world-class collection of motorcycles and cars.
3
Birmingham Museum of Art
Explore the extensive art collection. Admission is free.
4
Railroad Park
Enjoy the park in the heart of downtown Birmingham.
Tags
Des Moines to Birmingham
flights to Birmingham
driving to Alabama
I-35 and I-65 route
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Birmingham travel guide
Des Moines airport
Birmingham airport BHM
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travel tips
