Is there a train to Indianapolis?

No, there is no passenger rail service to Indianapolis.

Is Indianapolis walkable?

No, it is a car-dependent city.

How long is the drive?

The drive takes approximately 7 hours.

What is the best airport?

Indianapolis International Airport (IND) is the primary gateway.

Indianapolis is a very affordable city for lodging and dining.

Des Moines

Indianapolis

Driving

Des Moines to Indianapolis

Updated: 28 May 2026

The distance from Des Moines to Indianapolis is approximately 700 kilometers. Driving is the most practical mode of travel, taking about 7 hours via I-80 East and I-74 East. This is a straightforward drive through the heart of the Midwest. Indianapolis is known as the 'Crossroads of America' and is famous for the Indianapolis 500.

Total Distance: Driving distance 700 km, straight-line air distance 650 km.

Fastest Way

Driving via I-80 and I-74, taking approximately 7 hours.

Cheapest Way

Driving your own vehicle is the most cost-effective method.

Compare Des Moines to Indianapolis Routes

Driving

Direct

Duration

7 hours

Avg Price

$80 in fuel

Operator

Personal Vehicle

Route

I-80 E to I-74 E

The drive is very easy and well-maintained.

Travel Tips

Driving
The drive is very straightforward; follow the signs for I-74 East.
Walking
Indianapolis is a car-dependent city; plan to drive between attractions.
Safety
Stay alert during the drive and take regular breaks.
Dining
Try the local restaurants in the downtown area; they are excellent.
Planning
Use apps like Google Maps to navigate the city's layout.

Safety Tips

Road Safety
Be aware of changing weather conditions, especially during winter.
Emergency
Dial 911 for any emergencies; the city has a robust police presence.
Pedestrian Safety
Follow traffic signals, as Indianapolis traffic is generally moderate.
Health
Stay hydrated and take breaks, as the drive can be tiring.