Des Moines
Des Moines
Los Angeles
Los Angeles
Bus Flight

Des Moines to Los Angeles

Updated: 28 May 2026

Traveling from Des Moines to Los Angeles covers roughly 2,700 kilometers. The most efficient method is a flight from Des Moines International Airport (DSM) to Los Angeles International Airport (LAX). Alternatively, long-distance bus travel via Greyhound is possible but requires multiple transfers and over 40 hours of travel time. Driving involves taking I-80 West to I-15 South, a multi-day journey through the Rockies and the Mojave Desert. Los Angeles is a sprawling metropolis, so plan your local transport accordingly.

Total Distance: Driving distance 2,700 km, straight-line air distance 2,300 km.
Fastest Way
Flight with a connection, total travel time approximately 6-8 hours.
Cheapest Way
Bus travel is often cheaper, but flights are highly competitive when booked early.
Compare Des Moines to Los Angeles Routes
Bus
Connecting
Flight
Connecting
Duration 45 hours 4 hours
Avg Price $250 - $450 $200 - $500
Operator Greyhound United Airlines
Route Des Moines to LA via Omaha and Denver DSM to LAX
Tip Prepare for long layovers at major bus terminals. Most flights connect through Denver or Chicago.
Travel Tips
  • Traffic
    Avoid driving on the 405 freeway during rush hours (7-10 AM and 3-7 PM).
  • Public Transit
    Use the Metro Rail system to navigate between major hubs like Downtown and Hollywood.
  • Airport Access
    Use the FlyAway bus from LAX to reach Union Station cheaply.
  • Reservations
    Book popular restaurants and museum tickets weeks in advance.
  • Neighborhoods
    Research your destination neighborhood, as LA is extremely spread out.
Safety Tips
  • Vehicle Security
    Never leave valuables in your car, especially in tourist-heavy areas.
  • Pedestrian Safety
    Use designated crosswalks, as traffic in LA is fast and aggressive.
  • Emergency
    Keep a list of local police non-emergency numbers for your specific district.
  • Sun Exposure
    The California sun is intense; wear sunglasses and hats during outdoor activities.
People Also Ask
  • Is there a train to LA?
    No direct train exists; you would need to take a bus to a major Amtrak hub like Chicago.
  • How far is LA from Des Moines?
    It is approximately 2,700 kilometers by road.
  • What is the best way to get around?
    A rental car is the most practical way to see the city due to its size.
  • Are there direct flights?
    No, all flights from DSM to LAX currently require at least one connection.
  • Is LA expensive?
    Yes, accommodation and dining costs are significantly higher than in Iowa.
Quick Info
  • From Des Moines, Iowa, United States
  • To Los Angeles, California, United States
  • Modes
Best Time to Travel

September to November for mild weather and fewer crowds.

Things to Do in Los Angeles
1
Santa Monica Pier
Visit the historic pier for the Pacific Park amusement rides and ocean views. It marks the end of Route 66.
2
Griffith Observatory
Located in Griffith Park, it offers the best views of the Hollywood Sign and the city skyline. Admission to the grounds is free.
3
The Getty Center
Explore world-class art collections and stunning architecture perched on a hill. The tram ride up to the museum is an experience in itself.
4
Hollywood Walk of Fame
Walk along Hollywood Boulevard to see the stars of famous entertainers. It is a quintessential tourist stop.
Tags
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