Is there a direct train?

No, there is no direct passenger rail service between Des Moines and Nashville.

How long is the drive?

The drive takes approximately 12 hours depending on traffic and stops.

What is the best airport?

Nashville International Airport (BNA) is the primary hub for the city.

There are minimal tolls on this route depending on your specific path through Illinois.

Is it safe to drive alone?

Yes, the route is well-traveled and safe for solo drivers during daylight hours.

Des Moines

Nashville

Flight Driving

Des Moines to Nashville

Updated: 28 May 2026

The journey from Des Moines to Nashville covers approximately 1,100 kilometers across the American Midwest and South. Driving involves taking I-80 East to I-57 South, eventually merging onto I-24 East toward Nashville. Flights typically connect through hubs like Chicago O'Hare or St. Louis. You will traverse diverse landscapes ranging from Iowa cornfields to the rolling hills of Kentucky. This route is popular for those moving between the heartland and the music capital of the world.

Total Distance: 1,100 km driving distance; 920 km straight-line air distance.

Fastest Way

Flying is the fastest method, typically taking under 5 hours including layovers.

Cheapest Way

Driving is the most cost-effective option if traveling with more than one person.

Compare Des Moines to Nashville Routes

	Flight Connecting	Driving Direct
Duration	4 hours 30 mins	12 hours
Avg Price	$300-$500	$150-$250 in fuel
Operator	American Airlines	Personal Vehicle
Route	DSM to BNA via ORD or STL	I-80 E to I-57 S to I-24 E
Tip	Book your flight at least three weeks in advance to secure lower fares.	Stop in Paducah, Kentucky, to break up the final leg of your drive.

Travel Tips

Traffic Awareness
Avoid Nashville downtown traffic during rush hours between 7 AM and 9 AM.
Parking
Use the parking apps to find cheaper daily rates in downtown Nashville garages.
Weather
Nashville summers are humid; pack light, breathable clothing for your visit.
Airport Transit
The WeGo Public Transit bus route 18 connects the airport to downtown efficiently.
Booking
Always check flight prices on Tuesdays for the best mid-week deals.

Safety Tips

Road Safety
Watch for heavy semi-truck traffic on I-57 during night hours.
Downtown Safety
Stay in well-lit, populated areas when walking on Broadway at night.
Vehicle Security
Never leave valuables visible in your car when parked in public lots.
Emergency
Keep a physical road atlas in your car in case of cellular dead zones in rural Illinois.