Flight
Driving
Des Moines to Phoenix
Updated: 28 May 2026
The journey from Des Moines to Phoenix covers roughly 2,200 km. Flying from Des Moines International (DSM) to Phoenix Sky Harbor (PHX) is the most efficient route. Driving via I-80 and I-40 is a direct route. You will traverse the Great Plains and the desert.
Total Distance: Driving distance 2,250 km, air distance 1,900 km.
Fastest Way
Flight from DSM to PHX with a connection in Dallas.
Cheapest Way
Driving is the most cost-effective method for this distance.
Compare Des Moines to Phoenix Routes
|
Connecting
|
Direct
|
|
|---|---|---|
| Duration | 6 hours | 21 hours |
| Avg Price | $250 - $500 | $400 - $600 |
| Operator | American Airlines | Personal Vehicle |
| Route | DSM to PHX via DFW. | I-80 W to I-40 W. |
| Tip | Dallas is the primary hub for connections to Phoenix. | I-40 is the main artery through the desert. |
Travel Tips
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AirportPhoenix Sky Harbor (PHX) is easily accessible.
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WeatherPhoenix can be very hot in the summer; stay hydrated.
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DrivingBe aware of high temperatures in the desert.
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Local TransportA car is recommended for exploring the city.
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BookingBook flights at least 3 weeks in advance.
Safety Tips
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HeatStay hydrated during the summer months.
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DrivingAvoid driving through the desert during the hottest part of the day.
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Urban SafetyStay in well-populated areas when visiting downtown.
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EmergencyKeep plenty of water in your vehicle.
People Also Ask
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Is there a train?No direct Amtrak service from Des Moines to Phoenix.
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What is the best airport?Phoenix Sky Harbor (PHX).
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How long is the drive?Approximately 21 hours of driving time.
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Is Phoenix safe?Like any city, use common sense and stay aware.
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What is the climate?Desert with hot summers.
Quick Info
- From Des Moines, Iowa, United States
- To Phoenix, Arizona, United States
-
Modes
Best Time to Travel
Fall or Spring for pleasant temperatures in the desert.
Things to Do in Phoenix
1
Desert Botanical Garden
Features beautiful desert plants and landscapes. It is a must-visit.
2
Heard Museum
Features Native American art and history. It is a cultural landmark.
3
Papago Park
Features unique rock formations and hiking trails. It is a great place for a walk.
4
Phoenix Art Museum
Features extensive art collections. It is a popular destination.
Tags
Des Moines to Phoenix
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US travel guide
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