Des Moines
Des Moines
Pittsburgh
Pittsburgh
Flight Driving

Des Moines to Pittsburgh

Updated: 28 May 2026

The journey from Des Moines to Pittsburgh covers approximately 1,150 kilometers. Driving takes about 11 to 12 hours via I-80. Flying is also an option with connections. This route takes you through Illinois, Indiana, and Ohio, ending in the historic city of Pittsburgh at the confluence of three rivers.

Total Distance: 1,150 km driving, 1,000 km air distance.
Fastest Way
Flying is the fastest, taking about 5 hours including airport time.
Cheapest Way
Driving is the most cost-effective for this distance.
Compare Des Moines to Pittsburgh Routes
Flight
Connecting
Driving
Direct
Duration 5 hours 11 hours 30 mins
Avg Price $350-$550 $170-$240 in fuel
Operator United Airlines Personal Vehicle
Route DSM to ORD or PIT. I-80 East through Chicago, Toledo, and Cleveland.
Tip Book early to secure better rates on connecting flights. The Pennsylvania Turnpike is a toll road; have an E-ZPass ready.
Travel Tips
  • Public Transit
    The Pittsburgh Light Rail (the 'T') is a convenient way to get around downtown.
  • Dining
    Try the local Primanti Bros. sandwich; it is a Pittsburgh classic.
  • Parking
    Use the ParkWhiz app to find affordable parking in downtown Pittsburgh.
  • Safety
    Stick to well-lit, populated areas when exploring downtown at night.
  • Bridges
    Pittsburgh is known as the 'City of Bridges'; enjoy the unique architecture.
Safety Tips
  • Traffic
    Chicago traffic can be heavy; plan your route to avoid peak hours.
  • Weather
    The hilly terrain can make winter driving challenging; check forecasts before traveling.
  • Vehicle Security
    Always lock your car and remove valuables when parking in urban areas.
  • Emergency Kit
    Keep a basic emergency kit in your car for long-distance driving.
People Also Ask
  • Is there a train?
    No, there is no direct passenger rail service from Des Moines to Pittsburgh.
  • How long is the drive?
    Expect 11 to 12 hours of driving time.
  • Are there direct flights?
    No, flights from Des Moines to Pittsburgh require a connection.
  • Is Pittsburgh safe?
    Like any major city, exercise caution and stay in tourist-friendly areas.
  • What is the best route?
    I-80 is the most direct path.
Quick Info
  • From Des Moines, Iowa, United States
  • To Pittsburgh, Pennsylvania, United States
  • Modes
Best Time to Travel

May to October for pleasant weather and outdoor activities.

Things to Do in Pittsburgh
1
The Andy Warhol Museum
Visit the largest museum in North America dedicated to a single artist.
2
Duquesne Incline
Ride the historic funicular for stunning views of the city and the three rivers.
3
Point State Park
Explore the park at the confluence of the Allegheny, Monongahela, and Ohio rivers.
4
Carnegie Museum of Natural History
Discover the world-class dinosaur exhibits and other natural history collections.
Tags
Des Moines to Pittsburgh flights to Pittsburgh driving to Pennsylvania I-80 route travel Iowa to Pennsylvania Pittsburgh travel guide Des Moines airport Pittsburgh airport PIT Midwest road trip travel tips