No, there is no direct passenger rail service from Des Moines to Tulsa.

How long is the drive?

Expect 7 to 8 hours of driving time.

Are there direct flights?

No, flights from Des Moines to Tulsa require a connection.

Like any major city, exercise caution and stay in tourist-friendly areas.

What is the best route?

I-35 to US-69 is the most direct path.

Des Moines

Tulsa

Flight Driving

Des Moines to Tulsa

Updated: 28 May 2026

The journey from Des Moines to Tulsa covers approximately 750 kilometers. Driving takes about 7 to 8 hours via I-35 and US-69. Flying is also an option with connections. This route takes you through the Midwest and into the South, ending in the city of Tulsa.

Total Distance: 750 km driving, 650 km air distance.

Fastest Way

Flying is the fastest, taking about 3.5 hours including airport time.

Cheapest Way

Driving is the most cost-effective for this distance.

Compare Des Moines to Tulsa Routes

	Flight Connecting	Driving Direct
Duration	3 hours 30 mins	7 hours 30 mins
Avg Price	$200-$400	$100-$150 in fuel
Operator	American Airlines	Personal Vehicle
Route	DSM to DFW or TUL.	I-35 South to US-69 South through Kansas City.
Tip	Book early to secure better rates on connecting flights.	Kansas City is a great place to stop for a meal or a break.

Travel Tips

Public Transit
The Tulsa Transit bus system is a convenient way to get around Tulsa.
Dining
Try the local Southern-inspired cuisine; it is a Tulsa staple.
Parking
Use the ParkWhiz app to find affordable parking in downtown Tulsa.
Safety
Stick to well-lit, populated areas when exploring downtown at night.
History
Tulsa is rich in history; take a walking tour to learn more.

Safety Tips

Traffic
Traffic in the Tulsa area can be heavy; plan your route to avoid peak hours.
Weather
The South can have humid summers; stay hydrated.
Vehicle Security
Always lock your car and remove valuables when parking in urban areas.
Emergency Kit
Keep a basic emergency kit in your car for long-distance driving.